๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Ocular absorption of benzydamine by the rabbit

โœ Scribed by B. Catanese; P. Valeri; A. Lagana; L. Curini

Publisher
John Wiley and Sons
Year
1989
Tongue
English
Weight
175 KB
Volume
10
Category
Article
ISSN
0142-2782

No coin nor oath required. For personal study only.

โœฆ Synopsis

An aqueous solution of 0.15 per cent benzydamine hydrochloride, a non-steroidal antiinflammatory drug, was applied to the rabbit eye. Following topical application to the cornea, the drug was soon detected in the aqueous fluid of the treated eye, whereas the plasma levels were negligible. The possibility that benzydamine can inhibit inflammatory processes in the eye without the risk of side-effects is discussed.

๐Ÿ“œ SIMILAR VOLUMES

Ocular absorption of propranolol in rabb
Ocular absorption of propranolol in rabbits
โœ A. Hussain; S. Hirai; J. Sieg ๐Ÿ“‚ Article ๐Ÿ“… 1980 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 218 KB ๐Ÿ‘ 1 views
Improving the ocular absorption of pheny
Improving the ocular absorption of phenylephrine
โœ D. S. Chien; R. D. Schoenwald ๐Ÿ“‚ Article ๐Ÿ“… 1986 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 416 KB

An oxazolidine prodrug of phenylephrine and the base form of phenylephrine were synthesized, suspended in sesame oil, and tested for mydriatic activity against phenylephrine HCI. The HCI salt was formulated as a viscous aqueous solution and as a sesame oil suspension. A dosing volume of 10 pl was in

Ocular pharmacokinetics of a novel tetra
Ocular pharmacokinetics of a novel tetrahydroquinoline analog in rabbit: Absorption, disposition, and non-compartmental analysis
โœ Chandrasena R. Pamulapati; Ronald D. Schoenwald ๐Ÿ“‚ Article ๐Ÿ“… 2011 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 190 KB

The pharmacologically active compound (33% reduction in rabbit intraocular pressure recovery rate assay) 1-ethyl-6-fluoro-1,2,3,4-tetrahydroquinoline (MC4), which showed ocular hypotensive action and had optimum physicochemical properties, was characterized for its ocular absorption and distribution

Ocular pharmacokinetics of calcium, chlo
Ocular pharmacokinetics of calcium, chloride and sulphate ions after instillation in the rabbit
โœ C. Hariton; P. Mandel ๐Ÿ“‚ Article ๐Ÿ“… 1991 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 425 KB ๐Ÿ‘ 2 views

The ionic environment of the eye is involved in major biochemical processes which are essential for preserving the integrity of cornea and lens. The purpose of the present study was to determine the intra-ocular penetration and the pharmacokinetic parameters of calcium, chloride and sulphate ions in