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Octarepeat changes of prion protein in Parkinson's disease

✍ Scribed by Vinchi Wang; Tzu-Chao Chuang; Bing-Wen Soong; Din-E. Shan; Ming-Ching Kao

Book ID
116820490
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
349 KB
Volume
15
Category
Article
ISSN
1353-8020

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## Abstract Parkinson's disease (PD) is characterized by protein accumulation in the form of Lewy bodies and neurites. It is thus reasonable to consider that alterations in protein handling in the form of increased production, impaired clearance, or both might be central to the etiopathogenesis of