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OCs: ovarian cancer risk reduced in BRCA1/2 carriers


Book ID
120856002
Publisher
Adis International Limited (now part of Wolters Kluwer Health)
Year
2004
Weight
133 KB
Volume
&NA;
Category
Article
ISSN
1173-8324

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Germline mutations in BRCA1 and BRCA2 are associated with increased risks of breast and ovarian cancer. A genome-wide association study (GWAS) identified six alleles associated with risk of ovarian cancer for women in the general population. We evaluated four of these loci as potential modifiers of