Synthesis of [guanido-13C]-γ-hydroxyargi
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Goo Yoon; T. Mark Zabriskie; Seung Hoon Cheon
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Article
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2009
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John Wiley and Sons
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French
⚖ 94 KB
## Abstract This report describes an efficient method of synthesizing [guanido‐^13^C]‐__γ__‐hydroxyarginine HCl salt. Iodolactonization of __N__‐Boc‐protected allylglycine mainly provided the __cis__ iodo compound 2. This was converted to an amine through azide 4. The amine 5 was reacted with __N__