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Occurrence of heat-labile regan type of alkaline phosphatase in hematopoietic tumors

✍ Scribed by S. R. Damle; P. A. Shetty; D. J. Jussawalla; S. V. Bhide; A. J. Baxi

Book ID: 102863507
Publisher: John Wiley and Sons
Year: 1979
Tongue: French
Weight: 501 KB
Volume: 24
Category: Article
ISSN: 0020-7136
DOI: 10.1002/ijc.2910240404

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✦ Synopsis

Abstract

The physicochemical and immunological properties of alkaline phosphatase extracted from Hodgkin's nodes, non‐Hodgkin's lymphoma nodes and leukemic leukocytes have been studied. The alkaline phosphatase from these three tumor types possesses the same biophysical and biochemical properties and immunological determinants as the placental alkaline phosphatase. However, it is more heat‐labile than the placental isoenzyme. Immunological experiments indicate that, of these tumor types, Hodgkin's tumor contains the largest amounts of heat‐labile Regan type of alkaline phosphatase.

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