There is well documented evidence both in humans and in experimental animals that exposure to diethylstilbestrol (DES) during pregnancy results in an increased incidence of tumours in the progeny. The increased cancer risk has been reported to persist in the second generation descendants of DES-expo
โฆ LIBER โฆ
Occurrence of follicular cysts in thyroidectomized rats treated with diethylstilbestrol
โ Scribed by Janes, Ralph G.
- Publisher
- John Wiley and Sons
- Year
- 1944
- Tongue
- English
- Weight
- 924 KB
- Volume
- 90
- Category
- Article
- ISSN
- 0003-276X
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## Abstract Endocrine modulation of DMN carcinogenesis was studied in NZR/Gd rats preconditioned by starving 48 hr and then injected i.p. once with 20 mg DMN/kg. Intact rats developed kidney tumors (44% TBA), most of tubular epithelial type resembling human tumors rather than mesenchymal. Thyroidec