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Occurrence of a serine residue in the penicillin-binding site of the exocellular DD-carboxy-peptidase-transpeptidase from Streptomyces R61

✍ Scribed by Jean-Marie Frère; Colette Duez; Jean-Marie Ghuysen; Joel Vandekerkhove


Book ID
115906849
Publisher
Elsevier Science
Year
1976
Tongue
English
Weight
352 KB
Volume
70
Category
Article
ISSN
0014-5793

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An affinity gel matrix containing an enzyme (DD-peptidase) with specific p-lactam binding properties was characterized with respect to its binding and reactivity behavior with penicillin. The data show that immobilization of DDP by reaction with the enzymes susceptible amino groups resulted in chang