## BACKGROUND. The highly polymorphic HRAS1 minisatellite locus, located 1 kilobase downstream from the H-ras1 gene, has been associated with increased susceptibility to a variety of cancers. Microsatellite instability (MI), another molecular abnormality observed in human neoplasms, most likely re
Occupational risks for the development of brain tumors
β Scribed by Sara Kaplan; Shimon Etlin; Ilya Novikov; Baruch Modan
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 37 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0271-3586
No coin nor oath required. For personal study only.
β¦ Synopsis
Occupationally related risk factors were assessed in a population-based, case-control study of 139 patients with primary brain tumors (BT), carried out in central Israel between 1987-1991. For each case, two control groups were matched by age (65 years), sex, and ethnic origin. The interview schedule included questions about lifelong occupational history before diagnosis. Odds ratios (OR) for BT, according to industrial categories, showed a significantly increased risk among blue-collar workers, especially among those employed in the textile industry, and among drivers and motor vehicle operators. When histologic tumor types were assessed separately, a significantly increased risk for malignant BT was found among drivers and motor vehicle operator occupations, while for meningiomas, an increased risk was found among weavers and tailors. Our results may provide clues for etiology and prevention measures. Am.
π SIMILAR VOLUMES
An international case-control study of primary pediatric brain tumors included interviews with mothers of cases diagnosed from 1976 to 1994 and mothers of population controls. Data are available on maternal vitamin use during pregnancy for 1,051 cases and for 1,919 controls from 8 geographic areas i