Occupational, environmental, and life-style factors associated with the risk of hematolymphopoietic malignancies in women

✍ Scribed by L. Miligi; A. Seniori Costantini; P. Crosignani; A. Fontana; G. Masala; O. Nanni; V. Ramazzotti; S. Rodella; E. Stagnaro; R. Tumino; C. Viganò; C. Vindigni; P. Vineis

• Publisher: John Wiley and Sons
• Year: 1999
• Tongue: English
• Weight: 117 KB
• Volume: 36
• Category: Article
• ISSN: 0271-3586
• DOI: 10.1002/(sici)1097-0274(199907)36:1<60::aid-ajim9>3.0.co;2-z

✦ Synopsis

Background:

The etiology of lymphomas, leukemias, and multiple myeloma is still largely unknown. the known risk factors (ionizing radiation, solvent exposure, pesticide exposure, immunosuppression) explain only a small proportion of the cases that occur.

Methods:

We conducted a multicenter population-based case-control study on hematolymphopoietic malignancies in italy and interviewed 2,011 women (1,183 cases and 828 controls).

Results:

There was a suggestion of a positive association between smoking and the risk of non-hodgkin's lymphoma + chronic lymphocytic leukemia. a slight increased risk of leukemias was observed among women using permanent hair dye. housewives were at increased risk for leukemia and multiple myeloma. the risk of non-hodgkin's lymphomas + chronic lymphocytic leukemia, leukemias, multiple myeloma, and hodgkin's disease increased among women employed as hairdressers and textile workers. teachers were at increased risk for non-hodgkin's lymphomas + chronic lymphocytic leukemia, leukemias, and hodgkin's disease.

Conclusions:

These results confirm previous associations and may provide additional clues to some determinants of hematolymphopoietic malignancies in women.