Occupation, Tobacco Use, Coffee, and Bladder Cancer in the County of Mataro (Spain)

✍ Scribed by Carlos A. González; Gonzalo Lopez-Abente; Manuel Errezola; Jordi Castejón; Antonio Estrada; Monserrat Garcia-Milá; Pilar Gili; Mateo Huguet; Maria Serrat; Fátima Soler; Carlos Rodriguez

• Publisher: John Wiley and Sons
• Year: 1985
• Tongue: English
• Weight: 383 KB
• Volume: 55
• Category: Article
• ISSN: 0008-543X
• DOI: 10.1002/1097-0142(19850501)55:9<2031::aid-cncr2820550934>3.0.co;2-i

✦ Synopsis

This report presents the results of an epidemiologic case-control study. The study includes 58 cases and 116 controls from both sexes, selected from the Admission Register of the Hospital and from the Death Registry Office of the local city authorities. Controls have been matched to cases by age, sex, place of residence and source of selection. The results demonstrated no increased risk associated with coffee consumption. Habitual smokers present a 2.3 times higher risk than nonsmokers. The estimated relative risk for occupation standardized by age and smoking habit, is 5.5. A multiplicative effect of the simultaneous action of smoking and occupational exposure has been observed to be an estimated relative risk of 11.7. The attributable risk of the population has been estimated to be 39% for smokers and 12% for occupational exposure. A strong association was found between bladder cancer and occupational exposure to carcinogenic substances, especially in the dye and print textile industries.

Cancer 592031-2034, 1985.

T WAS APPROXIMATELY 100 years ago when Rehml

suggested the possible association of bladder cancer with occupational exposure in dye industry workers in Frankfurt and Basel. Later, it was statistically confirmed by Case c' f u/.? in the United Kingdom. Several casecontrol and some cohort studies3 conducted later showed the increased risk in leather worker^,^.^ chemical indusdye and print textile industries,* rubber and tire indu~tries.~~"' gas and petroleum refining workers,' ' wood workers,'* electric cable production worker^'^.'^ and metal workers.6 The International Agency for Research on Cancer published in 1982 a last supplement with a