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Occupation and histopathology of lung cancer: A case-control study in Rosario, Argentina

✍ Scribed by S.M. Pezzotto; L. Poletto

Publisher
John Wiley and Sons
Year
1999
Tongue
English
Weight
140 KB
Volume
36
Category
Article
ISSN
0271-3586

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✦ Synopsis

Background: Male age-adjusted lung cancer mortality rate is high in Rosario City, Argentina (62.7 per 100,000). Methods: Case-control study involving interviews with 367 male lung cancer patients and 576 controls. Results: The histological distribution detected was: squamous cell 39%, adenocarcinoma 34%, small cell carcinoma 13%, and other or no speci®ed cell type 14%. When comparing with the group unlikely to be exposed to occupational carcinogens, a 60% increase in risk was observed for the remaining occupations (P `0.008). Risks were high for drivers (OR 1.9, CI: 1.1±4.0), construction (OR 2.5, CI: 1.0±5.9), and agricultural workers also (OR 1.8, CI: 1.1±3.1). In regard to squamous cell carcinoma, increased risks were observed in the metal industry, particularly in welders (OR 2.9, CI: 1.0±10.1) and mechanics (OR 1.8, CI: 0.9±4.2). Smoking was not a substantial confounding effect. Conclusions: Occupational exposures partly account for the high lung cancer mortality rate among male residents of Rosario City. Am. J. Ind. Med. 36:437±443, 1999.

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