## Abstract Occult HBV infection is a wellβrecognised clinical entity characterised by the detection of HBVβDNA in serum and/or in liver in the absence of detectable hepatitis B surface antigen (HBsAg). Occult HBV infection has been described not only in patients who have resolved an acute or chron
β¦ LIBER β¦
Occult hepatitis B virus infection: a covert operation
β Scribed by F. B. Hollinger; G. Sood
- Book ID
- 108886395
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 532 KB
- Volume
- 17
- Category
- Article
- ISSN
- 1352-0504
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Genotype D occult hepatitis B virus (HBV) infections (OBIs) have a high frequency of amino acid substitutions in the major hydrophilic region of the small surface protein (S protein). This possibly reflects an escape mutation mechanism to evade detection by the host immune system. Mutations may also