Occlusion and infection in broviac catheters during intensive cancer therapy
✍ Scribed by Hillard M. Lazarus Md; James N. Lowder; Roger H. Herzig
- Publisher
- John Wiley and Sons
- Year
- 1983
- Tongue
- English
- Weight
- 700 KB
- Volume
- 52
- Category
- Article
- ISSN
- 0008-543X
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✦ Synopsis
Before administration of intensive cytotoxic therapy, 90 central venous catheters were inserted into 80 patients with malignancies. Twenty-seven episodes of bacteremia and fungemia occurred during 96 treatment courses. The majority of these infections were due to gram-positive bacteria (45%) or fungi (22%), although gram-negative organisms accounted for 33%. Catheter occlusion occurred in patients receiving intravenous phenytoin, but blood products could be infused without difficulty. An increase in grampositive bacteremias in patients with these catheters and drug-induced catheter occlusion must now be appreciated.