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OC-05 Inhibition of tissue factor by Ixolaris reduces primary tumor growth and metastasis in a murine model of melanoma

✍ Scribed by A. Da Silva de Oliveira; L.G. Lima; D.E. Machado; L.E. Nasciutti; L.C. Petersen; I.M.B. Francischetti; R.Q. Monteiro

Book ID: 117258198
Publisher: Elsevier Science
Year: 2010
Tongue: English
Weight: 51 KB
Volume: 125
Category: Article
ISSN: 0049-3848
DOI: 10.1016/s0049-3848(10)70040-2

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## Abstract Assessment of tumour vascularity may characterize malignancy as well as predict responsiveness to anti‐angiogenic therapy. Non‐invasive measurement of tumour perfusion and blood vessel permeability assessed as the transfer constant, __K__^trans^, can be provided by dynamic contrast‐enha