Observations on the intramolecular Heck reactions of aromatic chlorides using palladium/imidazolium salts

✍ Scribed by Stephen Caddick; William Kofie

• Publisher: Elsevier Science
• Year: 2002
• Tongue: French
• Weight: 173 KB
• Volume: 43
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(02)02340-7

✦ Synopsis

The intramolecular Heck reaction of aromatic amines and ethers using palladium/imidazolium salts is described. The use of tetra-n-butylammonium halide salts facilitates the reactivity of aromatic chlorides. An unexpected and novel palladiummediated cyclisation is also described leading to the formation of a tricyclic adduct.