𝔖 Bobbio Scriptorium
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Observations on preadipocytes and their distribution patterns in rat adipose tissue

✍ Scribed by E. W. Askew; S. T. Schuschereba; J. P. Brown; A. L. Hecker

Publisher
John Wiley and Sons
Year
1981
Tongue
English
Weight
817 KB
Volume
168
Category
Article
ISSN
0362-2525

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✦ Synopsis

Abstract

Microscopic examination of adipocytes isolated from adult rat epididymal adipose tissue revealed numerous small cells (< 10 ΞΌm) morphologically similar to larger adipocytes. These small adipocytes appear identical to a new classification of adipose cells termed preadipocytes. Electron micrographs of these preadipocytes revealed examples of cells < 10 ΞΌm in diameter in various stages of maturation and lipid accumulation. The percent distribution pattern of these small adipocytes was not significantly altered by exercise although exercise shifted the distribution patterns of the larger cells (> 30 ΞΌm) toward a smaller mean cell size. The quantitative significance of preadipocytes is not established but these preliminary observations indicate that adipocytes < 10 ΞΌm in diameter may account for a numerically greater proportion of the total adipocytes observed in collagenase isolated preparations than heretofore recognized, although their contribution to total adipose mass is probably negligible.

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