Observations on Indian node-negative breast cancer patients: A multivariate analysis

✍ Scribed by J. J. Vyas; P. B. Desai; M. B. Sampat; S. R. Shinde; D. N. Rao; Sudeep Sarkar; Rajan Badwe; J. Tiwari; A. Koppikar

• Publisher: John Wiley and Sons
• Year: 1989
• Tongue: English
• Weight: 635 KB
• Volume: 42
• Category: Article
• ISSN: 0022-4790
• DOI: 10.1002/jso.2930420411

✦ Synopsis

The modern treatment of breast cancer has evolved over the past 100 years based on clinical observations. Therapeutic principles, from the choice of surgical procedure to the management of disseminated disease, have also changed. The axillary tumour burden, that is, the number of histologically positive nodes (N + ) plays an important role as a prognostic factor. However, in histologically Negative nodes (N-), it is necessary to discriminate individuals at high risk despite negative nodes. This presentation analyses retrospectively the prognostic factors for long-term failures in Npatients. These prognostic factors need to be studied in detail, and controlled clinical trials should be carried out to detect high risk N-patients and consider them for adjuvant chemotherapy.