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Observational studies: going beyond the boundaries of randomized controlled trials

✍ Scribed by Wenying Yang; Alexey Zilov; Pradana Soewondo; Ole Molskov Bech; Fawzia Sekkal; Philip D. Home

Book ID
117371217
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
337 KB
Volume
88
Category
Article
ISSN
0168-8227

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Observational analogs of randomized clinical trials (RCTs) are well accepted in the study of disease risk factors, diagnosis, and prognosis. There is controversy about observational studies when the focus is on the intended benefit due to lack of blinding and poor control for unmeasured confounding.