## Abstract The hydrolysis of achiral and chiral esters by optically active poly(iminomethylenes), [R‐NC<]~__n__~, which contain imidazole groups in their side chains **R**, has been studied. The polymers include poly(L‐ and D‐carbylalanyl‐L‐histidine), **2d** and **2e**, poly(D‐carbylalanyl‐L‐his
✦ LIBER ✦
Observation of michaelis-menten kinetics in the hydrolysis of a phenyl ester catalyzed by an imidazole-containing polymer
✍ Scribed by Aso, Chuji ;Kunitake, Toyoki ;Shimada, Fumiko
- Publisher
- Wiley (John Wiley & Sons)
- Year
- 1968
- Tongue
- English
- Weight
- 178 KB
- Volume
- 6
- Category
- Article
- ISSN
- 0449-2986
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N-benzoyl-L-phenylalanyl-L-phenylalanine is an excellent peptide substrate for carboxypeptidase A; at 30°C and pH 7.5, K m is 2.6 × 10 -5 M while k cat is 177 s -1 (k cat /K m = 6.8 × 10 6 M -1 s -1 ). Indole-3-acetic acid is a noncompetitive or mixed inhibitor towards the peptide and toward hippury