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Observation of Duplex DNA-Drug Noncovalent Complexes by Electrospray Ionization Mass Spectrometry

โœ Scribed by Gale, David C.; Goodlett, David R.; Light-Wahl, Karen J.; Smith, Richard D.


Book ID
126954726
Publisher
American Chemical Society
Year
1994
Tongue
English
Weight
299 KB
Volume
116
Category
Article
ISSN
0002-7863

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Observation of noncovalent complexes to
โœ Brenda L. Schwartz; Karen J. Light-Wahl; Richard D. Smith ๐Ÿ“‚ Article ๐Ÿ“… 1994 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 370 KB

Intact avidin-biotin and avidin-biotin maleimide noncovalent complexes have been observed by electrospray ionization mass spectrometry (ESI-MS) by using an extended mass range quadrupole mass spectrometer. By utilizing mild ES1 interface conditions, the expected solution behavior of four biotin or b