Observation of circulating tumour cells in patients with non-small cell lung cancer by real-time fluorescent quantitative reverse transcriptase-polymerase chain reaction in peroperative period

New prognostic indicator for non-small-c

New prognostic indicator for non-small-cell lung cancer, quantitation of thymidylate synthase by real-time reverse transcription polymerase chain reaction

✍ Yasushi Shintani; Mitsunori Ohta; Hirohisa Hirabayashi; Hisaichi Tanaka; Keiji I 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 French ⚖ 202 KB

## Abstract Thymidylate synthase (TS) is an enzyme that catalyzes an important DNA biosynthesis process. The gene expression of TS has not been reported in non‐small‐cell lung cancer (NSCLC) patients. To clarify the correlation between TS mRNA levels and clinicopathological features of NSCLC, we ex