Exchange of amide protons with deuterium results in changes of 13 C chemical shifts for carbon atoms near the site of substitution (CH{N and N{C|O). There is a measurable decrease in the isotopic shifts of CH{N for cycloalkylacetamides as ring size increases from 3 to 8 and for lactams as ring size
β¦ LIBER β¦
Observation of chemical-shift effects in wide-line deuterium NMR
β Scribed by Thomas A Early
- Publisher
- Elsevier Science
- Year
- 1987
- Weight
- 520 KB
- Volume
- 74
- Category
- Article
- ISSN
- 0022-2364
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