Obligatory steps in protein folding and the conformational diversity of the transition state
β Scribed by Martinez, Jose C. ;Pisabarro, M. Teresa ;Serrano, Luis
- Book ID
- 109524298
- Publisher
- Nature Publishing Group
- Year
- 1998
- Tongue
- English
- Weight
- 779 KB
- Volume
- 5
- Category
- Article
- ISSN
- 1545-9993
- DOI
- 10.1038/1418
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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
The EF-hand motif, which assumes a helix-loop-helix structure normally responsible for Ca 2Ο© binding, is found in a large number of functionally diverse Ca 2Ο© binding proteins collectively known as the EF-hand protein superfamily. In many superfamily members, Ca 2Ο© binding induces a conformational c
All possible protein folding intermediates exist in equilibrium with the native protein at native as well as non-native conditions, with occupation determined by their free energy level. The study of these forms can illuminate the fundamental principles of protein structure and folding. Hydrogen exc