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Objective quantification of muscle and fat in human dystrophic muscle by magnetic resonance image analysis

✍ Scribed by Joanne Phoenix; Dibendu Betal; Neil Roberts; Timothy R. Helliwell; Richard H.T. Edwards

Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
980 KB
Volume
19
Category
Article
ISSN
0148-639X

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✦ Synopsis

Information about changes in muscle composition has to date been primarily restricted to histological examination of biopsy samples or qualitative assessment of images obtained using avariety of techniques (e.g., ultrasound, CT, and MRI). We describe the development of a quantitative method for the analysis of muscle composition using MR T, relaxation time mapping and image analysis. This approach provides an objective means of studying muscle and, when used in conjunction with force production measurements, may provide an accurate measure of response to muscle therapy. 0

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