Study of the prostaglandins led directly to the elucidation of the mode of action of aspirin which inhibits their synthesis. John Vane elegantly demonstrated in 1971 that non-steroid anti-inflammatory drugs (NSAIDs) blocked cyclooxygenase (COX), the enzyme which makes prostaglandins. In 1991, Daniel
✦ LIBER ✦
Obituary: John R. Vane (1927–2004)
✍ Scribed by Moncada, Salvador
- Book ID
- 109807688
- Publisher
- Nature Publishing Group
- Year
- 2005
- Tongue
- English
- Weight
- 164 KB
- Volume
- 433
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/433028a
No coin nor oath required. For personal study only.
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