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O642 - Association of the TNF −238 promoter polymorphism with susceptibility to tuberculosis and malaria in Africa

✍ Scribed by A.V.S. Hill; C. Ruwende; W. McGuire; R. Bellamy; E Coleman; S. Ali; H. Loke; T. Corrah; R. Snow; K. Marsh; B. Greenwood; K.J.W.P. McAdam; H.C. Whittle; D. Kwiatkowski

Book ID: 116115048
Publisher: Elsevier Science
Year: 1996
Tongue: English
Weight: 168 KB
Volume: 47
Category: Article
ISSN: 0198-8859
DOI: 10.1016/0198-8859(96)85337-7

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## Abstract ## Objective Single‐nucleotide polymorphisms (SNPs) of the tumor necrosis factor gene __TNF__ at positions −238 and −308 have been associated with psoriasis vulgaris and psoriatic arthritis (PsA). The strong linkage disequilibrium (LD) at chromosome region 6p21, a region known to harbo