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O36 Factors of imatinib resistance in chronic myeloid leukemia

✍ Scribed by B. Kajtár; D. Alpár; J. Tóth; R. László; P. Jáksó; L. Kereskai; Z. Nagy; L. Pajor

Book ID
104323066
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
49 KB
Volume
21
Category
Article
ISSN
0268-960X

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✦ Synopsis

Hb-Hana family is the first described example, where partial glutathione reductase deficiency represents a modifying factor of clinical manifestation of unstable hemoglobinopathy. Grant support: MSM 6198959205 and MSM 6198959216.

O35 A prognostic impact of transfusion dependency on survival of patients with early myelodysplastic syndrome

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## Abstract Although imatinib mesylate (IM) has revolutionized the treatment of chronic myeloid leukemia (CML), some patients develop resistance with progression of leukemia. Alternative or additional targeting of signaling pathways deregulated in bcr‐abl‐driven CML cells may provide a feasible opt