O3 Increased bone turnover in ankylosing spondylitis is associated with hypovitaminosis D and low bone mineral density
โ Scribed by S Shankar; Y Uday; M Pasha; A Handa
- Book ID
- 117689471
- Publisher
- Elsevier Science
- Year
- 2011
- Tongue
- English
- Weight
- 62 KB
- Volume
- 6
- Category
- Article
- ISSN
- 0973-3698
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๐ SIMILAR VOLUMES
The purpose of this study is to evaluate bone mineral density (BMD) and bone turnover markers in men with ankylosing spondylitis (AS) and to determine their relationship with clinical features and disease activity. Serum carboxi terminal cross-linked telopeptide of type I collagen (CTX), osteocalcin
## Summary Osteoporosis is a well recognized complication of ankylosing spondylitis (AS). This study indicates that increased bone turnover, inflammation, and low vitamin D levels are important in the pathophysiology of AS-related osteoporosis, and that bone turnover markers (BTM) are valuable mark
## Abstract The role of type 2 deiodinase (D2) in the human skeleton remains unclear. The D2 polymorphism Thr92Ala has been associated with lower enzymatic activity, which could result in lower local triiodothyronine (T~3~) availability in bone. We therefore hypothesized that the D2 Thr92Ala polymo