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O3-04-06 Structural and functional analysis of the Alzheimer's disease amyloid precursor protein copper binding domain

โœ Scribed by Roberto Cappai; Geoffrey Kong; William McKinstry; Denise Galatis; Julian Adams; Shane Bellingham; James Camakaris; Cyril Curtain; Nicholas Williamson; Anthony White; Konrad Beyreuther; Gerd Multhaup; Colin Masters; Kevin Barnham; Michael Parker


Book ID
117412771
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
164 KB
Volume
25
Category
Article
ISSN
0197-4580

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The โค-amyloid protein precursor (APP) has been extensively studied for its role in amyloid production and the pathogenesis of Alzheimer's disease (AD). However, little is known about the normal function of APP and its biological interactions. In this Mini-Review, the role of the cytoplasmic domain o