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O2-02-04 Increased α7 nicotinic acetylcholine receptor protein levels in Alzheimer's disease patients

✍ Scribed by Leung-wing Chu; Edmond S. Ma; Karen K. Lam; M.F. Chan; Daniel H. Lee


Book ID
117412682
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
158 KB
Volume
25
Category
Article
ISSN
0197-4580

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## Abstract Alzheimer's disease (AD) and dementia with Lewy bodies (DLB) are common forms of dementia in the elderly associated with cholinergic dysfunction, including reductions in nicotinic acetylcholine receptors (nAChRs). In AD, astrocytes are implicated in the formation of senile plaques, one