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O.192 Scavenger receptor class B type I is a co-receptor for infection with cell culture-derived hepatitis C virus

โœ Scribed by M.B. Zeisel; E.K. Schnober; A. Haberstroh; D. Lavillette; F. Cosset; T. Wakita; F. Stoll-Keller; H.E. Blum; H. Barth; T.F. Baumert

Book ID
117770217
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
142 KB
Volume
36
Category
Article
ISSN
1386-6532

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Scavenger receptor class B type I is a k
Scavenger receptor class B type I is a key host factor for hepatitis C virus infection required for an entry step closely linked to CD81
โœ Mirjam B. Zeisel; George Koutsoudakis; Eva K. Schnober; Anita Haberstroh; Hubert ๐Ÿ“‚ Article ๐Ÿ“… 2007 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 612 KB

Hepatitis C virus (HCV) is a major cause of chronic hepatitis worldwide. Scavenger receptor class B type I (SR-BI) has been shown to bind HCV envelope glycoprotein E2, participate in entry of HCV pseudotype particles, and modulate HCV infection. However, the functional role of SR-BI for productive H