O130. Transcriptome signature of the extracellular matrix and adhesion molecules in oral squamous cell carcinomas from sudanese N-nitrosamine rich toombak users

Mutations of the p53 gene in oral squamo

Mutations of the p53 gene in oral squamous-cell carcinomas from sudanese dippers of nitrosamine-rich toombak and non-snuff-dippers from the Sudan and Scandinavia

✍ Salah O. Ibrahim; Endre N. Vasstrand; Anne C. Johannessen; Ali M. Idris; Bengt M 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 French ⚖ 100 KB 👁 2 views

Using PCR-SSCP/DNA sequencing methods, we analyzed 14 oral squamous-cell carcinomas (OSCCs) and 8 premalignant oral lesions from different Sudanese patients for prevalence of mutations in exons 5 to 9 of the p53 gene in relation to toombak-dipping status. OSCCs (14 from Sudan, 28 from Scandinavia),