𝔖 Bobbio Scriptorium
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O1. Selective inactivators of cysteine proteinases inhibit bone resorption

✍ Scribed by Hill, PA; Buttle, D; Reynolds, JJ; Meikle, MC


Book ID
122717212
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
131 KB
Volume
15
Category
Article
ISSN
8756-3282

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## Abstract Incativators of cystein proteinases (CPs) were tested as inhibitors of bone resorption in vitro and in vivo. The following four CP inactivators were tested: Ep453, the membrane‐permeant produrg of Ep475, a compound with low membrane pereability which inhibits cathepsins B, L, S, H, and