Inhibition of bone resrption by selctive
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Peter A. Hill; David J. Buttle; Sheila J. Jones; Alan Boyde; Mitsuo Murata; John
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Article
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1994
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John Wiley and Sons
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English
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## Abstract Incativators of cystein proteinases (CPs) were tested as inhibitors of bone resorption in vitro and in vivo. The following four CP inactivators were tested: Ep453, the membraneβpermeant produrg of Ep475, a compound with low membrane pereability which inhibits cathepsins B, L, S, H, and