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O038 Role of human tolerogenic dendritic cell derived IL-35 in regulating T cell responses

✍ Scribed by K. Dixon; S. der Kooij van; N. Schlagwein; D.A. Vignali; C. van Kooten


Book ID
116400709
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
134 KB
Volume
59
Category
Article
ISSN
1043-4666

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## Abstract RNA interference technology has been used to modulate dendritic cell (DC) function by targeting the expression of genes such as IL‐12 and NF‐kB. In this paper, we demonstrate that transfectionof DC with IL‐10‐specific double strands of small interference RNA (siRNA) resulted in potent s