O-sulfinylation with methanesulfonyl cyanide or p-toluenesulfonyl cyanide and DBU.
β Scribed by Derek H.R. Barton; Joseph Cs. Jaszberenyi; Emmanouil A. Theodorakis
- Book ID
- 108380295
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- French
- Weight
- 211 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0040-4039
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π SIMILAR VOLUMES
Reaction of methanesulfonyl cyanide or p-toluenesulfonyl cyanide with carbon radicals generated from the acyl derivatives of N-hydroxy-2-thiopyridone gives the corresponding nitriles in high yield. A mechanistic scheme is suggested. There are many synthetic applications of carbon radicals generated
Electrophilic Cyanations. Part 2. Synthesis of Heteroarenecarbonitriles by Electrophilic Cyanation: Reaction of Metalated Heteroarenes with p-Toluenesulfonyl Cyanide. -Carefull regioselective lithiation of hetarenes or even arenes (I) followed by addition of Tos-CN gives fair yields of (hetero)aren