O-Silylated dienolates in organic synthesis: γ-Selective alkylation of unsaturated carbonyl compounds by 1,5-dithienium fluoroborate.

O-Silylated enolates in organic synthesi

O-Silylated enolates in organic synthesis: α-Alkylation of carbonyl compounds by 1,3-dithienium fluoroborate.

✍ Ian Paterson; Lee G. Price 📂 Article 📅 1981 🏛 Elsevier Science 🌐 French ⚖ 224 KB

S7.4mmary: The O-silylated enolates of ketones, aldehydes, esters, and lactones can be regiospecifically alkylated by 1,3-dithienium fluoroborate to give the selectivity protected S-dicarbonyl compounds. We have found that the reaction of O-silylated enolates with a-chloroalkyl phenyl sulphides (Ph