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[O-methyl-11C]β-CIT-FP, a potential radioligand for quantitation of the dopamine transporter: Preparation, autoradiography, metabolite studies, and positron emission tomography examinations

✍ Scribed by Camilla Lundkvist; Christer Halldin; Carl-Gunnar Swahn; Håkan Hall; Per Karlsson; Yoshifumi Nakashima; Shaoyin Wang; Richard A. Milius; John L. Neumeyer; Lars Farde

Book ID: 116172050
Publisher: Elsevier Science
Year: 1995
Tongue: English
Weight: 901 KB
Volume: 22
Category: Article
ISSN: 0969-8051
DOI: 10.1016/0969-8051(95)00029-w

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✍ Christer Halldin; Lars Farde; Camilla Lundkvist; Nathalie Ginovart; Yoshifumi Na 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 431 KB 👁 1 views

The cocaine analogue P-CIT-FE (N-(2-fluoroethyl)-2~-carbomethoxy-3~-(4-iodopheny1)nortropane) was labeled with ' lC for positron emission tomography (PET) studies of the dopamine transporter. After intravenous administration to a cynomolgus monkey, ["CIP-CIT-FE accumulated in the striatum with a str