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O-linked N-acetylglucosamine (O-GlcNAc) protein modification is increased in the cartilage of patients with knee osteoarthritis

✍ Scribed by Tardio, L.; Andrés-Bergós, J.; Zachara, N.E.; Larrañaga-Vera, A.; Rodriguez-Villar, C.; Herrero-Beaumont, G.; Largo, R.

Book ID: 122285289
Publisher: Elsevier Science
Year: 2014
Tongue: English
Weight: 676 KB
Volume: 22
Category: Article
ISSN: 1063-4584
DOI: 10.1016/j.joca.2013.12.001

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## Abstract ## Objective Bisphosphonates have slowed the progression of osteoarthritis (OA) in animal models and have decreased pain in states of high bone turnover. The Knee OA Structural Arthritis (KOSTAR) study, which is the largest study to date investigating a potential structure‐modifying OA