Biochemical regulation of breast cancer
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Hana Dolezalova; Geetha Shankar; Mei-Chuan Huang; Daniel D. Bikle; Edward J. Goe
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Article
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2003
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John Wiley and Sons
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English
β 310 KB
π 2 views
## Abstract G proteinβcoupled receptors (GPCRs) for lysophosphatidic acid (LPA) and sphingosine 1βphosphate (S1P) transduce signals to many functions of normal cells. Most human cancer cells upregulate S1P and LPA GPCRs, in patterns distinctive for each type of tumor. The findings that 1βalpha, 25β