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O-299 Enhanment of growth-inhibition and apoptosis in human lung cancer cells by combining low doses of celecoxib and N-(4-hydoxyphenyl)retinamide

✍ Scribed by Lotan, Rueben; Sun, Shi-Yong


Book ID
118571689
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
177 KB
Volume
41
Category
Article
ISSN
0169-5002

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## Abstract The synthetic retinoid fenretinide [N‐(4‐hydroxyphenyl)retinamide, 4‐HPR] has demonstrated growth inhibition and induction of apoptosis of various malignant cells, including lung cancer cell lines. 4‐HPR is now being investigated in several clinical trials. In our study, we show that 4‐