Nutritional factors and pancreatic cancer: A case-control study from South-West Poland

✍ Scribed by W. Zatonski; K. Przewozniak; G. R. Howe; P. Maisonneuve; A. M. Walker; P. Boyle

• Publisher: John Wiley and Sons
• Year: 1991
• Tongue: French
• Weight: 574 KB
• Volume: 48
• Category: Article
• ISSN: 0020-7136
• DOI: 10.1002/ijc.2910480314

✦ Synopsis

A population-based case-control study of diet and pancreatic cancer has been conducted in the Opole Voivodeship region in Poland, using I10 cases and 195 controls. A full diet history was used to estimate the daily intake of calories, fat, protein, carbohydrate, cholesterol, retinol, vitamin C, and fibre. There is a strong positive association with the intake of cholesterol with relative risks of I .90,3.77, and 4.3 I for the 3 upper quartiles compared with the lowest @. trend = <O.OI).

An inverse association was seen with vitamin C intake, with corresponding relative risks of 1.10, 0.30, and 0.37 (p, trend = cO.01). Weak inverse associations were seen with the intake of retinol and fibre. There is evidence of an inverse association with fat intake, particularly unsaturated fats, and of a positive association with the intake of carbohydrate and to a lesser extent, protein. These results further support the potential importance of dietary factors in the aetiology of cancer of the pancreas.