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NUP98Fusion in Human Leukemia: Dysregulation of the Nuclear Pore and Homeodomain Proteins

✍ Scribed by Takuro Nakamura


Book ID
111835405
Publisher
Carden Jennings Publishing
Year
2005
Tongue
English
Weight
513 KB
Volume
82
Category
Article
ISSN
0925-5710

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## Abstract The __NUP98__ gene at 11p15 is known to be fused to __DDX10, HOXA9, HOXA11, HOXA13, HOXD11, HOXD13, LEDGF__, __NSD1, NSD3, PMX1__, __RAP1GDS1__, and __TOP1__ in various hematologic malignancies. The common theme in all __NUP98__ chimeras is a transcript consisting of the 5β€² part of __NU