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Number of children and death from hormone-dependent cancers

✍ Scribed by Eiliv Lund

Publisher: John Wiley and Sons
Year: 1990
Tongue: French
Weight: 346 KB
Volume: 46
Category: Article
ISSN: 0020-7136
DOI: 10.1002/ijc.2910460608

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✦ Synopsis

The association between number of children of current marriage reported by 43 1.604 women aged 45-74 years at the Norwegian Census in 1970 and mortality, at follow-up through 1985, from hormone-dependent cancers, i.e., cancers of breast, corpus uteri and ovary combined, has been investiated. The reduction in age-adjusted mortality was 9.6% f 95% confidence interval; 8.3-10.9%) for each child with no deviation from linearity. Women with CII children had a relative risk of 0.34 (0.25-0.47) compared to nullipara. Adjustment for age at first birth slightly changed the effect of number of children on mortality to 9.3% per child. The reduction in mortality per child was for cancer of the breast 7.2%, corpus uteri 12.2% and ovary 12.7%. Our findings indicate that having few children is a major risk factor for death from the 3 hormone-dependent cancers combined.

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