𝔖 Bobbio Scriptorium
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(±)-Nuevamine, an isoindoloisoquinoline alkaloid, and (±)-lennoxamine, an isoindolobenzazepine

✍ Scribed by Emir Valencia; Alan J. Freyer; Maurice Shamma; Victor Fajardo


Publisher
Elsevier Science
Year
1984
Tongue
French
Weight
177 KB
Volume
25
Category
Article
ISSN
0040-4039

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A new approach to isoindolobenzazepines
✍ Yuji Koseki; Shuichi Kusano; Harumi Sakata; Tatsuo Nagasaka 📂 Article 📅 1999 🏛 Elsevier Science 🌐 French ⚖ 217 KB

A convenient short-step synthesis of lennoxamine 1 and chilenine 2 is described. The key steps are the preparation of an acyliminium ion precursor and a novel expansion of the six-membered ring to a seven-membered ring.