Nucléosides de synthèse XIV. Du choix des paramètres réactionnels pour l'obtention préférentielle de nucleosides en série benzoazole par réaction de fusion
✍ Scribed by Jean-Louis Barascut; Bernard L. Kam; Jean-Louis Imbach
- Book ID
- 112125163
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 1977
- Tongue
- English
- Weight
- 326 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0022-152X
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## Abstract The orientation of the cycloaddition of diazomethane on unsaturated branchedchain sugars has been studied. For 3‐__C__‐cyanomethylidene‐3‐deoxy‐1,2‐__O__‐isopropylidene‐α‐D‐__glycero__‐tetrofuranose the orientation was ‘normal’ and did not depend on the configuration at the double bond.
New aza heterocycles with benzimidazole, pyrazole and pyridine moieties in the same molecule have been prepared. Preliminary complexing properties with divalent copper salts were determined by means of mass spectrometry (FAB) and a very interesting oxydation reaction with molecular oxygen was shown.