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Nucleotide Sequence and Characterization of the 5′Flanking Region of the Rat Ha-ras Protooncogene

✍ Scribed by Giuseppe Damante, Sebastiano Filetti and Basil Rapoport

Book ID
123633782
Publisher
National Academy of Sciences
Year
1987
Tongue
English
Weight
746 KB
Volume
84
Category
Article
ISSN
0027-8424

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The complete 5' flanking region of the murine c-Ha-ras gene was cloned and sequenced. An untranslated exon (-1) was identified and the promoter region of the gene located. Like the rat and human homologues, the murine promoter is GC rich and contains several GC boxes together with a CAAT element, bu