## Abstract The authors investigated the possible correlations between the binding parameters, maximum binding capacity (__B__max) and dissociation constant (__K__d), of [^3^H]‐8 hydroxy‐2‐(di‐__N__‐propylamino) tetralin and [^3^H]‐imipramine in platelets of 13 healthy subjects. The __in vitro__ ph
✦ LIBER ✦
Nucleotide interactions with 5-HT1A binding sites directly labeled by [3H]-8-hydroxy-2-(di)-n-propylamino) tetralin ([3H]-8-OH-DPAT)
✍ Scribed by Jerry R. Schlegel; Stephen J. Peroutka
- Book ID
- 115779337
- Publisher
- Elsevier Science
- Year
- 1986
- Tongue
- English
- Weight
- 508 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0006-2952
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## Abstract The title compounds were synthesised in 7 steps from 1,7‐dihydroxynaphthalene as follows: 1,7‐dihydroxynaphthalene was methylated and subjected to a Birch reduction to yield 8‐methoxy‐2‐tetralone. Reductive amination with sodium cyanoboro[^3^H]hydride and n‐propylamine gave 8‐methoxy‐2‐
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