✦ LIBER ✦
Nucleosides and Nucleotides. Part 18. p-nitrobenzenesulfonyl nitroimidazole as a new condensing agent in the triester synthesis of oligonucleotides
✍ Scribed by Colin A. Leach; Felix Waldmeier; Christoph Tamm
- Book ID
- 102856633
- Publisher
- John Wiley and Sons
- Year
- 1981
- Tongue
- German
- Weight
- 513 KB
- Volume
- 64
- Category
- Article
- ISSN
- 0018-019X
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✦ Synopsis
Abstract
p‐Nitrobenzenesulfonyl nitroimidazole (p‐NBSNI) (5) has been shown to be an efficient and convenient condensing agent in the coupling of protected nucleotide fragments. Its utility has been demonstrated by a direct comparison with previously‐described condensing agents in the synthesis of various di‐ and tetradeoxy‐nucleotides.