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Nucleoside reverse transcriptase inhibitors (NRTIs)-induced expression profile of mitochondria-related genes in the mouse liver

โœ Scribed by Varsha G. Desai; Taewon Lee; Robert R. Delongchamp; Julian E.A. Leakey; Sherry M. Lewis; Fei Lee; Carrie L. Moland; William S. Branham; James C. Fuscoe


Book ID
116751772
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
215 KB
Volume
8
Category
Article
ISSN
1567-7249

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## Abstract It has been reported that a new pattern of mutations, E44D/A and/or V118I, in the reverse transcriptase (RT) gene of HIVโ€1 confers a moderate level of resistance to lamivudine in the absence of the M184V mutation. The prevalence of this mutational pattern was studied in HIVโ€1 isolates o