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Nucleophilic substitution in the series of (1,2,3-triazol-1-yl)-1,2,5-oxadiazoles. Reactions with N-, O-, and S-nucleophiles

โœ Scribed by V. Yu. Rozhkov; L. V. Batog; M. I. Struchkova


Publisher
Springer
Year
2005
Tongue
English
Weight
505 KB
Volume
54
Category
Article
ISSN
1573-9171

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## Abstract __N__โ€Silylated 3โ€acetoxyโ€1,2โ€thiazetidine 1,1โ€dioxide (5) is prepared from Lโ€cystine. Reactions of 5 with silyl enol ethers yield Cโ€3โ€substituted ฮฒโ€sultams 6, 12 and 15. Desilylation of 6 affords 7, which undergoes photochemical cyclization to give the bicyclic ฮฒโ€sultam 10. In the cour